5. The antihistamine, hydroxyzine is the best of these types of medications for itching in RSS.
6. Zyrtec, Xyzal, Allegra and Claritin are antihistamines that work better to help the symptoms of hay fever and sinusitis. They usually give minimal relief for itching in eczema.
7. Benadryl (nonprescription) works fairly well to ease the itching in children with eczema.
8. Topical Benadryl cream is not very effective for itching.